Financial Wire

ファイザーが今後実施するタファミディスの臨床試験は、非対称的な上昇余地を示しているとRBCキャピタル・マーケッツは述べている。

-- RBCキャピタル・マーケッツは月曜日のレポートで、ファイザー(PFE)のタファミディスに関する来週開始される臨床試験は、3つの主要な結果シナリオのモデリングに基づくと、非対称的な上昇余地があり、弱気シナリオと強気シナリオの間で50億ドルの正味現在価値の差が生じると指摘した。 同投資会社は、この訴訟は2035年に期限切れとなる「441多形体特許」にかかっており、「695化合物特許」と「696使用方法特許」が維持されると予想されるため、「科学的に最も弱い」と述べている。 RBCは、ファイザーが勝訴する確率を19%と推定しており、ファイザーが特許侵害を立証し、2035年まで特許保護を獲得した場合、正味現在価値は60億ドル以上になるとしている。 また、引き分けとなる確率は60%で、ジェネリック医薬品が2032年頃から参入した場合、正味現在価値は30億ドル以上になるとレポートは述べている。 さらに、ファイザーが訴訟に敗訴し、多形体特許が侵害されていないと判断される確率は21%であり、その場合、ジェネリック医薬品の市場参入は2028年になると見込まれる。これは現在、同社株に織り込まれている水準だとRBCは述べている。 RBCは同社株の投資判断を「アンダーパフォーム」に据え置き、目標株価を25ドルとした。

Price: $27.77, Change: $+0.21, Percent Change: +0.74%

Related Articles

Australia

Hasbro's Q1 Results to Focus on Wizards of the Coast Demand Strength, Cost Increases, UBS Says

Hasbro's (HAS) Q1 results will focus on strong demand in its Wizards of the Coast unit and how the company frames higher resin and freight costs for the profit and loss statement on a run-rate basis, UBS Securities said in a note Monday.UBS said demand strength in the Wizards of the Coast was driven by "Teenage Mutant Ninja Turtles," along with "Secrets of Strixhaven" showing strong presale numbers in Q1.UBS said that overall focus on margins is expected, given resin price inflation and freight and distribution cost increases, adding that it estimates every 10% rise in resin costs is around $0.08 in earnings per share, while every 10% increase in both inbound and outbound freight is around $0.09 of EPS for Hasbro.UBS added it expects Hasbro to keep its topline guidance for 2026, even if the company faces a slight supply chain disruption.UBS maintained its buy rating with a $110 price target.Price: $95.34, Change: $-1.81, Percent Change: -1.86%

$HAS
Oil & Energy

Crude Flows via Hormuz Shrink, Refinery Margins Tighten Despite Ceasefire, Rystad Says

Global crude markets are tightening further as oil shipments via the Strait of Hormuz continue to fall, deepening a supply shock that traders had hoped was easing after last week's brief pullback in Brent prices, Rystad Energy strategists said in a note Monday."Friday's Brent complex sell-off on Trump's reopening announcement offered some relief. Margins clawed back, and on some North Sea, West African, and Black Sea grades, the numbers briefly looked workable again," Paola Rodriguez-Masiu, chief oil analyst at Rystad, said.Physical crude costs have surged well beyond futures benchmarks, with Dated Brent averaging above $20 per barrel in April and physical differentials plus freight adding another $20 to $ 25, pushing replacement-crude economics into unworkable territory for many refiners.Rystad said some traders interpreted last week's Brent retracement as a sign that the worst of the disruption had passed. However, the underlying physical constraints have not improved.Rodriguez Masiu said the acute phase is not behind us. "Europe needs more product, and the refineries capable of producing it are cutting runs. The rational response at the refinery level would be catastrophic at the system level," she said.Oil shipments via the Hormuz have dropped since the outbreak of the Middle East conflict.Rystad said April is on track for a deeper disruption than March, with Middle East Gulf production averaging 14.3 million b/d, about 3 million b/d below last month and over 13 million b/d short of pre-war levels.The consultancy said shipments at alternative outlets, Yanbu, Fujairah, and Ceyhan, have hit record highs at a combined 6.8 million b/d, but only 4.2 million b/d of that is incremental supply, far short of replacing lost volumes.Flows improved in early April as a dual-corridor opened through Iranian and Omani waters, and Iraqi loadings ticked higher. However, traffic deteriorated again after the Apr. 8 ceasefire, despite Iran's announcement that it would reopen the Strait.With a US naval blockade still restricting ships entering or leaving Iranian ports, Rystad notes that the last remaining flows, largely Iranian crude and condensate, are now drying up.Peace talks are expected to continue ahead of the ceasefire's expiry on Apr. 22, but Rystad said even a swift resolution would not restore supply immediately.The consultancy forecasted that it would take until July for flows to recover to 80-90% of pre-war levels, and another one to two months before those barrels reach refineries as finished products.The tightening has driven the Dated-to-Frontline Brent spread to about $25/bbl, reflecting the extreme premium for barrels available for immediate loading."A market this short will not flatten gently," Rodriguez Masiu said. "It will correct through higher prompt prices, and the longer the refinery margin squeeze runs, the sharper that correction will need to be."

Oil & Energy

Trump Says US Blockade to Remain Until Deal

US President Donald Trump on Monday reiterated on Truth Social that the US blockade would remain in force until a deal is reached and that Iran was forcing vessels toward the US for oil."The Iranian leadership has forced hundreds of ships toward the United States, mostly Texas, Louisiana, and Alaska, to get their oil," Trump posted.In multiple posts on Truth Social, Trump said that the blockade would not be lifted until there is a deal, claiming that Iran was losing $500 million per day, describing the loss as "unsustainable."Regarding the military effort, Trump said, "things are going very well," and that the US was winning the war "by a lot."He posted that he was facing "no pressure" on Iran talks and said the potential agreement would be "far better" than the Joint Comprehensive Plan of Action, also known as the Iran nuclear deal, criticizing the prior deal as one of the worst arrangements for US national security.In another post on Truth Social, Trump said that Democrats are attempting to undermine the US position in negotiations with Iran, while insisting he will not rush into an unfavorable agreement."I'm not going to let them rush the United States into making a deal that is not as good as it could have been," Trump said, rejecting claims of urgency.He dismissed media reports and added that talks could conclude "relatively quickly," while maintaining he is focused on securing stronger terms than previous agreements.